The Blood Moon

'The Blood Moon is the most powerful upgrader in all of existence. Provides a random upgrade between 5x and 20,000x.'

This is currently the best upgrader in Ore Mania as of the 1.7 update.

The Blood Moon is an Infernal tier Upgrader that multiply the value of your ore by a minimum of x5 and a maximum of x20k. This item is obtainable by rebirthing at any life with a chance of 1/7k.